Pterovita®

Overview

Pterovita® is a highly bioavailable form of pterostilbene developed by CIRCE Scientific® through cocrystal engineering.

By combining pterostilbene with picolinic acid, it significantly enhances bioavailability. It is reported to achieve 9.9 times higher blood levels than standard pterostilbene, allowing a lower dose to be used for an equivalent effect.

The formulation is reported to offer potential benefits for cognitive function, antioxidant activity, skin protection against radiation, and DNA repair and cellular health.

Applications

CIRCE Scientific® offers science-based solutions and ingredients to the food supplement, food and beverage, animal health and pharmaceutical industries.

Pterovita® is highly versatile and can be seamlessly integrated into diverse product formats.

Key features

Picolinic acid is a compound naturally produced in the human body. It is a derivative of the amino acid tryptophan and is known to support the body’s mineral absorption and immune response.

Combining pterostilbene with picolinic acid is reported to achieve 9.9 times higher blood levels compared to standard pterostilbene.

It has been reported to increase the dissolution rate more than 35-fold and to raise solubility in different media 2–5 times.

Thanks to increased absorption and availability in the body, it is reported to have a greater impact on cellular processes, including those involving DNA.

Antioxidant properties: It helps protect DNA from oxidative damage caused by free radicals. By scavenging free radicals and reducing oxidative stress, it may contribute to maintaining genomic integrity.

Sirtuin activation: It supports the activation of proteins that regulate cellular processes such as DNA repair, gene expression and aging.

Mechanism of action

Pterostilbene is a poorly water-soluble compound with limited absorption.

In Pterovita®, pterostilbene is combined with picolinic acid through cocrystal engineering. This cocrystal structure increases the dissolution rate of pterostilbene more than 35-fold and raises its solubility in different media 2–5 times.

The increased solubility makes it possible to reach 9.9 times higher blood levels compared to standard pterostilbene. High bioavailability strengthens the effect on DNA repair and cellular processes and supports sirtuin activation.