Probi Osteo®

Overview

In most people under the age of 30, the continuous formation and breakdown of bone tissue (remodeling) follows a balanced pattern. After the age of 30, however, this balance is disrupted: bone loss exceeds formation, and bone density gradually decreases.

Probi® Osteo is a probiotic concept based on a combination of the Lactiplantibacillus plantarum HEAL9 (HEAL9™), Lactiplantibacillus plantarum HEAL19 and Lacticaseibacillus paracasei 8700:2 strains, clinically documented to support bone health.

Applications

Probi® Osteo is suitable for capsules and stick packs, as well as for functional foods such as beverages and powder products.

Key features

It is based on the Lactiplantibacillus plantarum HEAL9 (HEAL9™), Lactiplantibacillus plantarum HEAL19 and Lacticaseibacillus paracasei 8700:2 strains.

It is reported to help maintain bone density and mineral content.

It supports the natural balance of bone remodeling.

Related publications:

Jansson P-A. et al. “Probiotic treatment using a mix of three Lactobacillus strains for lumbar spine bone loss in postmenopausal women: a randomised, double-blind, placebo-controlled, multicentre trial.” The Lancet Rheumatology 2019;1(3):e154-e162.

Lawenius L. et al. “A probiotic mix partially protects against castration-induced bone loss in male mice.” J Endocrinol 2022;254(2):91-101.

Ohlsson C. et al. “Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice.” Am J Physiol Endocrinol Metab 2021;320(3):E591-E597.

Sophocleous A. et al. “Probiotics Inhibit Cartilage Damage and Progression of Osteoarthritis in Mice.” Calcified Tissue International 2023;112(1):66–73.